3-Part & 5-Part Automated Hematology Analyzer with CRP & SAA

3-Part & 5-Part Automated Hematology Analyzer with CRP & SAA
3-Part & 5-Part Automated Hematology Analyzer with CRP & SAA
PM-C531
Point of origin
ISO13485 ISO9001
Testing item
CBC CRP & SAA
Throughput
100T/H
Application scenarios
lab,science,hospital,CDC
Sample
blood

The PM-C531 Automated 3-Part & 5-Part Hematology Analyzer with CRP & SAA is a flexible and high-throughput clinical device designed for comprehensive hematological analysis. It can switch between 3-part and 5-part differential modes with a single touch, providing detailed analysis along with CRP and SAA measurements.

Technical Parameters

  • Modes: Switchable between 3-Part and 5-Part differential mode.

  • Combined Analysis: Hematology + CRP + SAA.

  • Throughput: High throughput of 100 tests per hour.

  • Report Parameters:

    • Five-Part Mode: 29 report parameters.

    • Three-Part Mode: 21 report parameters.

  • Detection Technologies:

    • Laser Scatter Light Detection and 3D Analysis: Detects different angle scatter light information of cells; 3D scattergram helps separate cell clusters to detect abnormal cells.

    • Semiconductor Laser Flow Cytometry: Detects white blood cells and basophils, and provides five-part WBC statistical counts.

    • Sheath Flow Impedance Technology: Measures the number and volume distribution of red blood cells and platelets.

    • Colorimetry: Measures hemoglobin concentration.

    • Immunoturbidimetric Unit: Converts light signals through detected liquid into electrical signals, processes them to obtain the concentration of measured objects, and calculates the results of remaining parameters.

  • Sample Types:

    • Venous whole blood

    • Peripheral whole blood

    • Pre-diluted blood

    • Serum (for immune projects)

    • Sample volumes: Whole blood ≤70μL, trace whole blood ≤38μL, pre-dilution ≤20μL.

  • Reagents:

    • Diluent

    • Hemolytic agents (HGB hemolytic agent, BASO hemolytic agent, DIFFⅠ hemolytic agent, DIFFⅡ hemolytic agent)

    • Immunoturbidimetric reagent

    • Probe cleaning solution


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  1. Advanced Detection Technologies:

    • Laser Scatter Light Detection and 3D Analysis: Provides detailed cell morphology and helps in detecting abnormal cells by analyzing scatter light information from different angles.

    • Semiconductor Laser Flow Cytometry: Accurate detection of white blood cells and basophils, offering precise five-part WBC counts.

    • Sheath Flow Impedance Technology: Measures red blood cell and platelet counts and volume distribution accurately.

    • Colorimetry: Provides reliable hemoglobin concentration measurements.

    • Immunoturbidimetric Unit: Measures CRP and SAA concentrations accurately by converting light signals into electrical signals for precise quantification.

  2. Comprehensive Reporting:

    • 29 Parameters in Five-Part Mode: Detailed analysis and reporting.

    • 21 Parameters in Three-Part Mode: Sufficient for less complex analyses.

  3. Minimal Sample Volume:

    • Low Sample Volume Requirements: ≤70μL for whole blood, ≤38μL for trace whole blood, and ≤20μL for pre-diluted blood, allowing for efficient use of small samples.

  4. Wide Range of Samples:

    • Versatility: Compatible with venous whole blood, peripheral whole blood, pre-diluted blood, and serum samples for a wide range of applications.

  5. Environmentally Friendly:

    • Cyanide-Free Methods: Uses environmentally safe techniques for hemoglobin and other measurements.

Clinical Applications

  1. Routine Hematology Testing:

    • Provides comprehensive blood cell counts and differentials essential for routine check-ups and diagnosing various hematological conditions.

  2. Inflammatory Marker Detection:

    • Measures CRP and SAA levels to diagnose and monitor inflammatory conditions, infections, and autoimmune disorders.

  3. Anemia and Hemoglobinopathy Diagnosis:

    • Accurate measurement of red blood cells, hemoglobin, and reticulocytes helps in diagnosing different types of anemia and other hemoglobinopathies.

  4. Thrombocytopenia Evaluation:

    • Dual platelet counting methods (impedance and fluorescence) ensure precise platelet counts, critical for evaluating thrombocytopenia.

  5. Infection and Immune Status Monitoring:

    • Detailed WBC differentiation aids in diagnosing and monitoring infections, immune responses, and hematological malignancies.

  6. Bone Marrow Function Assessment:

    • Reticulocyte count provides insight into bone marrow activity and helps in diagnosing bone marrow disorders.

  7. Pre-surgical and Post-surgical Monitoring:

    • Essential for evaluating patients' hematological status before and after surgery to ensure optimal recovery and detect any complications.

  8. Chronic Disease Management:

    • Regular monitoring of hematological parameters in patients with chronic diseases like diabetes, cardiovascular diseases, and kidney diseases helps in managing and adjusting treatments effectively.

  9. Pediatric and Geriatric Care:

    • Suitable for use in vulnerable populations such as children and the elderly due to its low sample volume requirements and high accuracy.


Key technologiesLaser flow cytometry, sheath flow impedance technology, colorimetry
Detection light sourceSemiconductor laser
WBC/Baso detection methodCytochemical staining/optical method
Red blood cell and platelet detection principleSheath flow impedance method
HGB detection methodEnvironmentally friendly cyanide-free HGB measurement
CRP detectionImmunoscattering turbidimetry
Detection modeFive-category mode: 7 measurement modes (CBC, CBC+DIFF, CBC+DIFF+CRP, CBC+DIFF+CRP+SAA, CRP+SAA, CRP, SAA);
Three-category mode
Report parametersFive categories: 29 report parameters; Three categories: 21 report parameters
Research parametersFive categories: 8 items (ALY#, ALY%, LIC#, LIC%, NRBC#, NRBC%, PDW-CV , NLR); three-category: 1 item (PDW-CV)
Image parametersFive-category (2 three-dimensional scatter plots - DIFF, WBC/BASO, 5 two-dimensional scatter plots - 3 DIFF plots, 2 WBC/BASO plots, 3 histograms - WBC/BASO, RBC, PLT)
Three-category (3 histograms - WBC, RBC, PLT)
Specimen modeVenous whole blood, peripheral whole blood, pre-diluted blood, serum (for immune items)
Detection range and precisionWBC: (3.5-15) × 109/L, CV≤2.0%
RBC: (3.5-8)×1012/L, ≤1.5%
HGB: (100-180)g/l, ≤1%
MCV: (70-120)fl, ≤1%
HCT: (35-50)%, ≤1.5%
PLT: (100-500)×109/L, ≤4%
CRP: ≤10mg/L, SD≤0.5mg/L;>10mg/L, CV≤4%
Detection speedCBC: 100 samples/hour
CBC + DIFF: 100 samples/hour
CBC + DIFF + CRP: 90 samples/hour
CBC+DIFF + CRP + SAA: 60 samples/hour
CRP + SAA: 60 samples/hour
CRP: 90 samples/hour
SAA: 90 samples/hour
Three categories: 100 samples/hour
Required sample volumeWhole blood: ≤70μL, trace whole blood: ≤38μL, pre-dilution: ≤20μL
Data transmission standard interfaceSupport HL7 protocol, automatic barcode scanning method
Display screen/computerRequired to be equipped with a computer, PC: x86 architecture processor host; CPU: 1.6G or above dual-core processor; resolution: ≥1920*1080; memory: ≥4GB; hard disk: ≥128GB; operating system win7 and above, 64-bit
Supporting reagentsDiluent, hemolytic agent (HGB hemolytic agent, BASO hemolytic agent, DIFFⅠ hemolytic agent, DIFFⅡ hemolytic agent), immunoturbidimetric reagent, probe cleaning solution


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